The pain originating in temporomandibular joint or the masticatory muscles is suspected when the pain is localised to this region and occurs with functions such as speaking or eating or mouth opening along with a click noise from within the joint.

The temporomandibular region pain is usually managed by a trigger point injection of masticatory muscles if trigger points are located on these muscles or a diagnostic temporomandibular joint injection with a local anaesthetic with or without a steroid under fluoroscopic guidance.