Central pain syndrome is a neurological condition caused by damage or malfunction in the Central Nervous System (CNS) which causes a sensitization of the pain system. The extent of pain and the areas affected are related to the cause of the injury.
Damage to the CNS can be caused by car accidents, limb amputations, trauma, spinal cord injury, tumors, stroke, immune system disorders or diseases, such as Multiple Sclerosis, Parkinson's, Graves or Addison's disease, Rheumatoid arthritis, and epilepsy.It may develop months or years after injury or damage to the CNS.